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Temporal and longitudinal analysis of Danish Swine Salmonellosis Control Programme data: implications for surveillance

机译:丹麦猪沙门氏菌病控制计划数据的时空和纵向分析:监测的意义

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摘要

The control programme for Salmonella infection in Danish swine has reduced the number of human cases attributable to pork consumption and the focus is now on cost-effectiveness. We applied time-series and longitudinal analyses to data collected between January 1995 and May 2005 to identify if there were predictable periods of risk that could inform sampling strategy; to investigate the potential for forecasting for early aberration detection; and to explore temporal redundancy within the sampling strategy. There was no evidence of seasonality hence no justification to change to targeted sampling at high-risk periods. The forecast of seropositivity made using an ARIMA (0, 1, 2) model had a root-mean-squared percentage error criterion of 8·4% indicating that accurate forecasts are possible. The lorelogram identified temporal redundancy at up to 10 weeks suggesting little value in sampling more frequently than this on the ‘average’ farm. These findings have practical applications for both farm-level sampling strategy and national-level aberration detection which potentially could result in a more cost-effective surveillance strategy.
机译:丹麦猪沙门氏菌感染的控制计划减少了可归因于猪肉消费的人类病例数,现在的重点是成本效益。我们对1995年1月至2005年5月之间收集的数据进行了时间序列和纵向分析,以确定是否存在可预测抽样策略的可预测风险期。调查预测早期像差检测的潜力;并探索采样策略内的时间冗余。没有证据表明存在季节性因素,因此没有理由在高风险时期更改为目标抽样。使用ARIMA(0,1、2)模型进行的血清反应阳性预测的均方根百分比误差标准为8·4%,这表明可以进行准确的预测。线性关系图确定了长达10周的时间冗余,这表明在“平均”农场中进行更频繁采样的价值很小。这些发现在农场级抽样策略和国家级像差检测中都有实际应用,可能会导致更具成本效益的监视策略。

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